With Windows, the problem of the registry is always the same. Over time, over installations, uninstalls, windows update: there is a degradation of the registry.
Personally, once every 2 years (even years):
A big full backup
I list all programs on printer
For all software with licenses =>
I disable them one by one
Then I unmount them
For others I do not do anything
I get the latest ISO image at Windows
I recover the possible updates of the drivers
I have my key for Windows 10 PRO
And finally, I format my HDD OS for a clean install
then I have 1 days to install all software important.
And I have a brand new and powerful system.