While the Global End feature can be set to bigger number there are issues with other stuff: ie
i have a sequence 1845142-1845168.dpx [TC: 20:30:05:17 - 20:30:06:18]. Duration of 26 frames.
In preferences>General > frame starts from->sequence (provides TC no. in TrimIn/Out fields)
So i copied and pasted TrimOut to Composition Global End. It works - so far so good.
Next step - i'm copying TrimIn to Loader Global In - and a bummer!
Loader Global In and Out are set / limited to 1000000 (and every Creator node i guess - i checked a few of them and that was the case!)
Composition Render Start is 1000000 and Render End is 1000026. Composition Global End is still 1845168
i think that is what Kaspar had in mind.
If not - here's another bug