ohimbz wrote:Creating optimized media defeats the purpose of having a powerful PC that can edit real time the given format!
I also have a 1080Ti which have none of the issues above, with the exception of being much slower in compute .. can't even dream of the realm where a node with Noise Reduction can be even played real time.
So don't try. What can I say

I didn't propose it to use it, but to locate the source of the problem.
Try disabling performance mode...
I just color graded Sony XAVC 500 mbps 4:2:2 50 fps footage (think it was a Sony FS7) that was cut into a hundred ever-shorter and sped-up edits and saw no such behavior in Resolve 16 (my rig is in my sig), although I did have some frame skipping because the rig is borderline for 50 fps. Once optimized it worked really well