NUMA enable or disable?

The most recent versions of Avid have enabled a warning to disable NUMA.
I didn't see anything about this in the config guide, does anyone know if DaVinci cares about this setting?
Asking specifically in regards to a system at my office (that we can't have be unreliable)
Windows 10 1709
Xeon E5-2697 v4 (x2)
128 GB RAM
GTX 1080 (x3)
I didn't see anything about this in the config guide, does anyone know if DaVinci cares about this setting?
Asking specifically in regards to a system at my office (that we can't have be unreliable)
Windows 10 1709
Xeon E5-2697 v4 (x2)
128 GB RAM
GTX 1080 (x3)