resolve 14.3.1 not executing on MAC PRO after High Sierra

Hi
My machine
Mac Pro 5,1 running the latest version of High Sierra
Nvidia Quadro 4000 GPU (cuda 2 compliant)
Nvidia Gforce GTX 120 video card
(latest Nvidia driver and cuda all supported)
Deck Link extreme 3d I/o latest driver all up to date with blackmagic
Tangent Wave control surface with V1.2 firmware
32 gig ram
8tb raid
FSI monitor
Decklink SDI-HDMI converter
Panasonic Plasma client monitor
Ultrascopes
I was running OSX Mountain Lion, and all was fine for years. Then I had to use Premier 2018 edition and went to High Sierra, absolute nightmare. Had to replace GPU (from FX4800 cuda 1.3) USB3 PCIe Adaptor (from Cal Digit) - not supported under HS and/or by manufacturer anymore. Anyhow this should work, bog standard set up, been over these blogs and other looking for the answer, so I'm reaching out.
In either 14.5 or 12.5 Resolve the software will not load, quits after "looking for control surface'
Any ideas, has anybody had this problem.
Any clues or directions warmly received
cheers
Paul
My machine
Mac Pro 5,1 running the latest version of High Sierra
Nvidia Quadro 4000 GPU (cuda 2 compliant)
Nvidia Gforce GTX 120 video card
(latest Nvidia driver and cuda all supported)
Deck Link extreme 3d I/o latest driver all up to date with blackmagic
Tangent Wave control surface with V1.2 firmware
32 gig ram
8tb raid
FSI monitor
Decklink SDI-HDMI converter
Panasonic Plasma client monitor
Ultrascopes
I was running OSX Mountain Lion, and all was fine for years. Then I had to use Premier 2018 edition and went to High Sierra, absolute nightmare. Had to replace GPU (from FX4800 cuda 1.3) USB3 PCIe Adaptor (from Cal Digit) - not supported under HS and/or by manufacturer anymore. Anyhow this should work, bog standard set up, been over these blogs and other looking for the answer, so I'm reaching out.
In either 14.5 or 12.5 Resolve the software will not load, quits after "looking for control surface'
Any ideas, has anybody had this problem.
Any clues or directions warmly received
cheers
Paul