In looking at your video closer, I notice you are using Fusion 3D with quite a few image planes... and I notice rendering is slow generally. I believe audio cutouts are normal in such cases.
I vaguely recall, not sure... that there's some option to prioritize whether audio can be skipped or not in situations like that (i.e., I think by default it will skip if audio won't sound good... but that may be adjustable, check docs or someone else can clarify).
I do a few things when having issues, depending on the issue. But generally, I will try to adjust optimization settings for the context, meaning read up on DR optimization features/options that affect Timeline and Fusion playback, tweak as necessary.
Sometimes I prerender areas that will not change much to remove the need for resources on those areas. I definitely do this if I must have smooth playback amidst a fairly reader-heavy clip that can be safely prerendered (again, something that you are finished working on... or are okay with not editing at the moment... you can always swap out a prerender for original as needed).
If something weird and "buggy" seems to be happening, like media missing but the media is not missing, I will exit DR, manually delete my cache, restart and that often clears oddball issues up.
On one system, I have about 0.5TB free and sometimes my optimization settings are too high quality for the need and disk space unnecessarily gets very low... I exit, delete the cache and tweak my cache defaults.
Offhand, from your video, I'd say try purging cache, read up on the DR/Fusion optimization options, ensure you're not using "too much" of anything during playback.
Oh, maybe check out the DR troubleshooting FAQ:
viewtopic.php?f=21&t=90190