Pretty much what's in the subject.
I had two fusion compositions which were starting to bog down my machine on 18 beta 4. Hoping to free up some cycles I opted for "render in place". While it *did* generate a rendered copy and replaced the comp in the timeline, that turned into a one way ticket. The original composition is now empty.
This happened with two compositions.
Alas, upgrading to 18 beta 5 didn't bring anything back from the dead.