Eddy Juillerat wrote: using the right tool is the key.
So, right away I ran into a line-frequency beat on a practical lighting element in a drama, so it was "on." The MedianNR approach makes for a very noise-free flicker... but doesn't fix the flicker.
What worked was the BCC restoration package "deFlicker" using the eyedropper to qualify the offending element (because it did not affect the whole frame, as a timelapse exposure presents) and then worked through analysis modes (RGB worked). It adds a "zero" to the render time... but happy client, beat the deadline.
jPo