Phillip Lakis wrote: Even at 4k gaming a 4x slot only loses 4-10fps.
What works for gaming isn't necessarily going to translate to Resolve.
You cpu/mobo combo doesn't have sufficient lanes to do what you want.
On that particular board, only the 16x/8x slots are routed directly to the cpu (the only GPU's that Resolve can see).
The R9 270 in the 4x slot is routed through the PCH/Southbridge chip first before continuing to the CPU. The PCH also handles all your SATA, USB, M.2 data to the CPU all within the same 4x lane constraint.
You need to leave these 4x lanes open for read/write media to your drives.
If your want an Intel 170 based motherboard capable of more lane capacity, you need to get one with a PLX chip. Like this one:
https://www.asus.com/us/Motherboards/Z170-WS/or
drop more $$$ and upgrade to X99 mobo's.